The main prison buildings were built as an orphanage in the 1890s which closed in 1956. The site opened as a women's prison in 1962 when female prisoners from Strangeways were transferred in.
From 1983 Young Offenders were admitted and in 1999 a wing was added to accommodate unsentenced female prisoners following the closure of Risley's remand centre, increasing the prison size by 60%.
The prison was featured in the BBC2 documentary ‘Women on the Edge – the Truth about Styal Prison' on February 27th 2006.

